The Immunology Laboratory services at St Helier Hospital and St George’s Hospital are merging to form a single service at St George’s Hospital with the Protein Reference Unit. Below is a summary of changes and improvements as a result of forming the new service. For more information, please contact the Immunology Laboratory using the contact details below.
General enquiries: 020 8725 0025; stgh-tr.stgeorgespru@nhs.net
Clinical enquiries: 020 8725 5106; immunologyclinicalenquiries@stgeorges.nhs.uk (secure domain)
Immunology Manager: Laura Kirsopp 020 8725 1918
SWLP Immunology Clinical Lead/Director Protein Reference Unit: Dr Rachel Wheeler 020 8725 1870.
Summary of changes
Changes to reference range, method and/or units
| Assay | Units | Reference range | Method |
| MPO antibodies | IU/ml | 0-5.9 | Bioflash immunoassay |
| PR3 antibodies | IU/ml | 0-4.9 | Bioflash immunoassay |
| GBM antibodies | CU | 0-19.9 | Bioflash immunoassay |
| dsDNA antibodies | IU/ml | 0-35 | Bioflash immunoassay |
| ENA antibodies* (Ro52, Ro60, Sm, RNP) | CU | <20 | Bioflash immunoassay |
| Centromere antibodies* | CU | <20 | Bioflash immunoassay |
| Complement C3 | g/L | 0.9-1.8 | BNII rate nephelometer |
| Complement C4 | g/L | 0.10-0.40 | BNII rate nephelometer |
| Rheumatoid factor | IU/ml | 0-16 | BNII rate nephelometer |
| Alpha-1 antitrypsin concentration | g/L | No change | BNII rate nephelometer |
Analyser upgrades
Optilite for Serum free light chains & IgD
Capillarys 3 Octa for serum protein electrophoresis
Bioflash analyser for autoantibodies
Following the changes, the above assays are unaccredited and are part of an Extension to Scope for the ISO15189:2012 accreditation due in June 2023