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Immunology and Protein Reference Unit

Someone reviewing an immunology test result

The Immunology Laboratory and Protein Reference Unit is a specialist service based at St George’s Hospital. It provides a comprehensive diagnostic service for immunology across the South West London Pathology network. The department hosts one of two Supraregional Assay Service Protein Reference Units

The Immunology Laboratory and Protein Reference Unit is a specialist service based at St George’s Hospital. It provides a comprehensive diagnostic service for immunology across the South West London Pathology network. The department hosts one of two Supraregional Assay Service Protein Reference Units in England and serves an extensive client base nationally and internationally, receiving samples from over 100 referring hospitals.

The Protein Reference Unit was established in 1971 under Professor J.R.Hobbs at Westminster Hospital, London. Professor Hobbs was an expert in the analysis of serum proteins, including immunoglobulins. After a brief relocation in 1992 to the Royal Surrey County Hospital at Guildford, the Protein Reference Unit settled at St George’s Hospital.

The Protein Reference Unit maintains its specialist interest and skills in protein analysis, particularly relating to immunoglobulins, including cryoglobulins and heavy chain disease investigations.

The wide and diverse UKAS-accredited repertoire of tests carried out by the Immunology Laboratory and Protein Reference Unit help to exclude, diagnose and monitor a variety of immunologically-based diseases including:

  • allergy
  • immune deficiency
  • hematological malignancy
  • autoimmune disease.

Expert advice is available from our Consultant Clinical Scientist team around appropriate investigation of clinical problems and the interpretation of results. This includes encouraging the most appropriate use of immunology tests and ensuring our service develops to meet changing clinical requirements.

in England UK and serves an extensive client base nationally and internationally, receiving samples from over 100 referring hospitals.

The Protein Reference Unit was established in 1971 under Professor J.R.Hobbs at Westminster Hospital, London. Professor Hobbs was an expert in the analysis of serum proteins, including immunoglobulins. After a brief relocation in 1992 to the Royal Surrey County Hospital at Guildford, the Protein Reference Unit settled at St George’s Hospital.

The Protein Reference Unit maintains its specialist interest and skills in protein analysis, particularly relating to immunoglobulins, including cryoglobulins and heavy chain disease investigations.

The wide and diverse UKAS-accredited repertoire of tests carried out by the Immunology Laboratory and Protein Reference Unit help to exclude, diagnose and monitor a variety of immunologically-based diseases including:

  • allergy
  • immune deficiency
  • hematological malignancy
  • autoimmune disease.

Expert advice is available from our Consultant Clinical Scientist team around appropriate investigation of clinical problems and the interpretation of results. This includes encouraging the most appropriate use of immunology tests and ensuring our service develops to meet changing clinical requirements.

Meet our team of consultants

Find our more about the Immunology team at Epsom and St Helier Hospitals

Contact details

Immunology Laboratory and Protein Reference Unit
South West London Pathology
St George’s Hospital
Tooting
London SW17 0QT

Clinical advice

020 8725 5106
ImmunologyLabSWLP@stgeorges.nhs.uk

Main laboratory

020 8725 0025
ImmunologyLabSWLP@stgeorges.nhs.uk.

SWLP Immunology Clinical Lead

Rachel Wheeler
020 8725 5106
rachel.wheeler@stgeorges.nhs.uk

Immunology Manager

Laura Kirsopp
020 8725 6182
laura.kirsopp@stgeorges.nhs.uk

Latest news

July 27, 2026

Learning from Bordeaux: shaping the future of our GP hub

Our managing director, Simon Brewer, led a team from the South West London to Bordeaux, France to visit one of Europe’s most advanced diagnostic laboratories, a trip that is now directly shaping plans for SWLP’s own GP hub.

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July 8, 2026

New test codes for requesting immunoglobulins – Epsom and St Helier hospitals and GPs only

Immunoglobulin and serum protein electrophoresis requesting is changing on 8 July 2026. Clinicians can now request immunoglobulins only or immunoglobulins and electrophoresis. This change will enable doctors to more effectively request the tests that are clinically indicated and streamline laboratory testing, delivering improved turnaround times for these tests. This change will apply to Epsom & St Helier Hospitals and their associated GPs initially, and will then be rolled out to all service users in south west London.

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June 12, 2026

Kim Brown: gesh celebrating an NHS leader and mentor 27 years in the making!

After 27 years of dedicated service to the NHS, Kim Brown, Technical Lead in Biochemistry, has finally received the recognition she richly deserves through the gesh Long Service Awards.

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June 8, 2026

From Milton Keynes to Network Lead: Sewa Joacquim-Hearne on collaboration, chaos, and a career in blood transfusion

Just three weeks into her new role as Blood Transfusion (BT) Network Lead for SWLP, Sewa Joacquim-Hearne is already on the move. Based at St George’s Hospital but with a presence planned across all five sites, including Epsom, St Helier, Kingston, and Croydon, she is taking on a role that is as much about connection as it is about clinical expertise.

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