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Immunology and Protein Reference Unit

The Immunology Laboratory and Protein Reference Unit is a specialist service based at St George’s Hospital. It provides a comprehensive diagnostic service for immunology across the South West London Pathology network. The department hosts one of two Supraregional Assay Service Protein Reference Units in England UK and serves an extensive client base nationally and internationally, receiving samples from over 100 referring hospitals.

The Protein Reference Unit was established in 1971 under Professor J.R.Hobbs at Westminster Hospital, London. Professor Hobbs was an expert in the analysis of serum proteins, including immunoglobulins. After a brief relocation in 1992 to the Royal Surrey County Hospital at Guildford, the Protein Reference Unit settled at St George’s Hospital.

The Protein Reference Unit maintains its specialist interest and skills in protein analysis, particularly relating to immunoglobulins, including cryoglobulins and heavy chain disease investigations.

The wide and diverse UKAS-accredited repertoire of tests carried out by the Immunology Laboratory and Protein Reference Unit help to exclude, diagnose and monitor a variety of immunologically-based diseases including:

  • allergy
  • immune deficiency
  • hematological malignancy
  • autoimmune disease.

Expert advice is available from our Consultant Clinical Scientist team around appropriate investigation of clinical problems and the interpretation of results. This includes encouraging the most appropriate use of immunology tests and ensuring our service develops to meet changing clinical requirements.

Latest news

July 15, 2021

A day in the life… Diana Mohanaraja

Find out more about a day in the life of Biomedical Support Worker and soon to be Biomedical Scientist Diana Mohanaraja.

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June 2, 2021

A new study shows that previous Covid-19 infection protects against reinfection even without antibodies

A new study carried out using existing laboratory test data shows that people who had a positive PCR test for Covid-19 but a negative serology test, meaning that they did not produce detectable antibodies, still had a significant amount of protection from reinfection.

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May 10, 2021

Epsom and St Helier University Hospitals and South West London Pathology announce new pathology partnership

Epsom and St Helier University Hospitals NHS Trust and South West London Pathology are announcing the formation of a new pathology partnership for south west London and beyond.

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April 6, 2021

SWLP says a sad farewell to virologist Dr David Carrington

The end of March marked the retirement of St George’s Hospital Virologist Dr David Carrington.

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