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Immunology and Protein Reference Unit

The Immunology Laboratory and Protein Reference Unit is a specialist service based at St George’s Hospital. It provides a comprehensive diagnostic service for immunology across the South West London Pathology network. The department hosts one of two Supraregional Assay Service Protein Reference Units in England UK and serves an extensive client base nationally and internationally, receiving samples from over 100 referring hospitals.

The Protein Reference Unit was established in 1971 under Professor J.R.Hobbs at Westminster Hospital, London. Professor Hobbs was an expert in the analysis of serum proteins, including immunoglobulins. After a brief relocation in 1992 to the Royal Surrey County Hospital at Guildford, the Protein Reference Unit settled at St George’s Hospital.

The Protein Reference Unit maintains its specialist interest and skills in protein analysis, particularly relating to immunoglobulins, including cryoglobulins and heavy chain disease investigations.

The wide and diverse UKAS-accredited repertoire of tests carried out by the Immunology Laboratory and Protein Reference Unit help to exclude, diagnose and monitor a variety of immunologically-based diseases including:

  • allergy
  • immune deficiency
  • hematological malignancy
  • autoimmune disease.

Expert advice is available from our Consultant Clinical Scientist team around appropriate investigation of clinical problems and the interpretation of results. This includes encouraging the most appropriate use of immunology tests and ensuring our service develops to meet changing clinical requirements.

Latest news

May 4, 2022

SWLP Point of Care Testing Team runs first community diagnostic outreach clinic

South West London CCG ran their first diagnostic outreach clinic in the community supported by our Point of Care Testing (POCT) team testing at-risk groups for diabetes. The clinic was run at a Shree Ghanapathy Temple in Wandsworth where 34 members of the community were tested. Of that 34, 32 had abnormal results and two […]

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April 5, 2022

Reducing blood product wastage at Croydon Hospital

The team in Blood Transfusion at Croydon Hospital have been working hard to reduce wastage of blood products. They have been doing this by reassessing the holding stock levels, rotation of stock and usage of short-dated units. Procedural changes were put in place in December 2020 and there has already been a significant reduction in […]

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March 23, 2022

Pledia FIT testing system goes live in Microbiology

The Pledia Faecal Immunochemical Testing (FIT) system has now gone live in Microbiology. The new analyser can process 320 samples in an hour and 200 samples can be loaded at one time.

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February 3, 2022

Immunology article published in the Annals of Clinical Biochemistry

Some of our team in Immunology and PRU have had an article published in the Annals of Clinical Biochemistry. The article looks at how one of the newest myeloma drugs interfered with monitoring of a myeloma patient at the St George’s Hospital.

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