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Immunology and Protein Reference Unit

The Immunology Laboratory and Protein Reference Unit is a specialist service based at St George’s Hospital. It provides a comprehensive diagnostic service for immunology across the South West London Pathology network. The department hosts one of two Supraregional Assay Service Protein Reference Units in England UK and serves an extensive client base nationally and internationally, receiving samples from over 100 referring hospitals.

The Protein Reference Unit was established in 1971 under Professor J.R.Hobbs at Westminster Hospital, London. Professor Hobbs was an expert in the analysis of serum proteins, including immunoglobulins. After a brief relocation in 1992 to the Royal Surrey County Hospital at Guildford, the Protein Reference Unit settled at St George’s Hospital.

The Protein Reference Unit maintains its specialist interest and skills in protein analysis, particularly relating to immunoglobulins, including cryoglobulins and heavy chain disease investigations.

The wide and diverse UKAS-accredited repertoire of tests carried out by the Immunology Laboratory and Protein Reference Unit help to exclude, diagnose and monitor a variety of immunologically-based diseases including:

  • allergy
  • immune deficiency
  • hematological malignancy
  • autoimmune disease.

Expert advice is available from our Consultant Clinical Scientist team around appropriate investigation of clinical problems and the interpretation of results. This includes encouraging the most appropriate use of immunology tests and ensuring our service develops to meet changing clinical requirements.

Latest news

July 1, 2022

Refurbished Immunology and ED laboratories at St George’s Hospital get official opening

This week, the newly refurbished Immunology and Emergency Department (ED) laboratories at St George’s Hospital were officially opened by Trust Managing Director Kate Slemeck and Chief Operating Officer Anne Brierley. A ribbon cutting was held at each laboratory and Kate and Anne were given a tour around the refurbished spaces by laboratory staff. The Immunology […]

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June 24, 2022

HIV service at Croydon Hospital wins ‘Top Global Winner’ at the UNIVANTS awards

This week, it was announced that work to improve HIV outcomes at Croydon Hospital was awarded ‘Top Global Winner’ at the UNIVANTS 2021 awards. The work focused on the introduction of ‘opt-out’ HIV testing in the Emergency Department at Croydon Hospital, with a sustained rate of 97% over 18 months, setting an international gold standard. […]

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June 20, 2022

Immunology services across south west London to be centralised at the Immunology Laboratory at St George’s Hospital

All Immunology services and tests are moving to the South West London Pathology (SWLP) Immunology Laboratory and Protein Reference Unit at St George’s Hospital, which will become the hub for immunology across south west London. Already one of the largest immunology services in the country, the team will be expanded further when immunology services and […]

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May 16, 2022

Point of Care Testing (POCT) at St George’s gets first UKAS accreditation

Last month, the SWLP POCT team received the exciting news that after two years of hard work, the blood gas and glucose meter service at St George’s was given full UKAS accreditation. It is the largest and most complex POCT service in the country to receive full accreditation, which proved challenging for both the POCT […]

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