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Immunology and Protein Reference Unit

Someone reviewing an immunology test result

The Immunology Laboratory and Protein Reference Unit is a specialist service based at St George’s Hospital. It provides a comprehensive diagnostic service for immunology across the South West London Pathology network. The department hosts one of two Supraregional Assay Service Protein Reference Units

The Immunology Laboratory and Protein Reference Unit is a specialist service based at St George’s Hospital. It provides a comprehensive diagnostic service for immunology across the South West London Pathology network. The department hosts one of two Supraregional Assay Service Protein Reference Units in England and serves an extensive client base nationally and internationally, receiving samples from over 100 referring hospitals.

The Protein Reference Unit was established in 1971 under Professor J.R.Hobbs at Westminster Hospital, London. Professor Hobbs was an expert in the analysis of serum proteins, including immunoglobulins. After a brief relocation in 1992 to the Royal Surrey County Hospital at Guildford, the Protein Reference Unit settled at St George’s Hospital.

The Protein Reference Unit maintains its specialist interest and skills in protein analysis, particularly relating to immunoglobulins, including cryoglobulins and heavy chain disease investigations.

The wide and diverse UKAS-accredited repertoire of tests carried out by the Immunology Laboratory and Protein Reference Unit help to exclude, diagnose and monitor a variety of immunologically-based diseases including:

  • allergy
  • immune deficiency
  • hematological malignancy
  • autoimmune disease.

Expert advice is available from our Consultant Clinical Scientist team around appropriate investigation of clinical problems and the interpretation of results. This includes encouraging the most appropriate use of immunology tests and ensuring our service develops to meet changing clinical requirements.

in England UK and serves an extensive client base nationally and internationally, receiving samples from over 100 referring hospitals.

The Protein Reference Unit was established in 1971 under Professor J.R.Hobbs at Westminster Hospital, London. Professor Hobbs was an expert in the analysis of serum proteins, including immunoglobulins. After a brief relocation in 1992 to the Royal Surrey County Hospital at Guildford, the Protein Reference Unit settled at St George’s Hospital.

The Protein Reference Unit maintains its specialist interest and skills in protein analysis, particularly relating to immunoglobulins, including cryoglobulins and heavy chain disease investigations.

The wide and diverse UKAS-accredited repertoire of tests carried out by the Immunology Laboratory and Protein Reference Unit help to exclude, diagnose and monitor a variety of immunologically-based diseases including:

  • allergy
  • immune deficiency
  • hematological malignancy
  • autoimmune disease.

Expert advice is available from our Consultant Clinical Scientist team around appropriate investigation of clinical problems and the interpretation of results. This includes encouraging the most appropriate use of immunology tests and ensuring our service develops to meet changing clinical requirements.

Meet our team of consultants

Find our more about the Immunology team at Epsom and St Helier Hospitals

Contact details

Immunology Laboratory and Protein Reference Unit
South West London Pathology
St George’s Hospital
Tooting
London SW17 0QT

Clinical advice

020 8725 5106
ImmunologyLabSWLP@stgeorges.nhs.uk

Main laboratory

020 8725 0025
ImmunologyLabSWLP@stgeorges.nhs.uk.

SWLP Immunology Clinical Lead

Rachel Wheeler
020 8725 5106
rachel.wheeler@stgeorges.nhs.uk

Immunology Manager

Laura Kirsopp
020 8725 6182
laura.kirsopp@stgeorges.nhs.uk

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February 12, 2026

All immunology samples should now be sent in yellow top blood tubes

The SWLP Immunology laboratory is installing new pre-analytic equipment to increase sample capacity and streamline workflows. As a result, all Immunology samples should be collected into yellow top blood tubes (serum separator tube/SST), as indicated on sample labels.

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