Login to South West London Pathology Services

If you have any queries about pathology consumables – you need a new account or you have a query about your order, please telephone 020 8266 6827. Forgotten your password

SWLP to introduce Enhanced Liver Fibrosis (ELF™) Test

At the beginning of 2021, South West London Pathology (SWLP) will be introducing the Enhanced Liver Fibrosis (ELF™) Test from Siemens to our repertoire. The test can initially be requested by GPs in the borough of Wandsworth.

The (ELF™) test, which has been developed by Siemens Healthineers, can be used to identify patients with mild to moderate liver fibrosis (usually asymptomatic) in patients with chronic liver disease, allowing clinicians to intervene before significant, irreversible damage occurs. Main causes of liver fibrosis include:

  • hepatitis (HBV and HCV) infection
  • alcohol abuse
  • non-alcoholic liver disease (NAFLD).

As a result of the increasing rates of obesity, NAFLD is now the commonest cause of abnormal liver function tests in the UK, with a third of the population affected. Ten to thirty percent of these patients will develop progressive liver disease, ultimately resulting in cirrhosis. Staging fibrosis is essential in all patients with NAFLD to identify subjects with advanced fibrosis who are at risk of liver-related complications.

TheELF™test is a simple blood test, which can be performed on a single serum sample, to diagnose NAFLD patients at risk of advanced liver fibrosis, without the need for resource-intensive scans or invasive biopsies. Patients diagnosed with mild fibrosis using the ELF™ test can be managed in primary care, while those diagnosed with moderate fibrosis can then be referred to specialists for more detailed investigation of the severity of their condition and treatment.

Evidence from the UK, published in the Journal of Hepatology, indicates that  a two-step testing pathway involving standard laboratory liver function tests and ELF™, leads to an 81% reduction in unnecessary referrals, which reduces time and money spent on secondary care investigations.

SWLP Consultant Clinical Scientist and lead on ELF™ testing Sarah Davie says, “The ELF™ test is a relatively simple and quick test which has the potential to have benefits for both the patient and the health service.

“As the number of patients developing NAFLD continues to rise, the ELF™ test means that we can quickly identify those with moderate fibrosis, allowing interventions to be put in place to reduce the progression of the disease.”

Find out more about the ELF™ test through this educational video

Latest news

November 4, 2022

Immunology services at St George’s and Epsom and St Helier Hospitals merging

Immunology services at St George’s and Epsom and St Helier Hospitals are merging into one service, which will be located at St George’s Hospital. This is taking place during October and November. 

Read more
October 17, 2022

Microbiology services at SWLP live with a new Laboratory Information Management System

Microbiology at SWLP successfully went live with the new system on Monday 10 October. This marks a significant achievement for teams within SWLP and across the four trusts who have worked extremely hard to make this happen.

Read more
July 1, 2022

Refurbished Immunology and ED laboratories at St George’s Hospital get official opening

This week, the newly refurbished Immunology and Emergency Department (ED) laboratories at St George’s Hospital were officially opened by Trust Managing Director Kate Slemeck and Chief Operating Officer Anne Brierley. A ribbon cutting was held at each laboratory and Kate and Anne were given a tour around the refurbished spaces by laboratory staff. The Immunology […]

Read more
June 24, 2022

HIV service at Croydon Hospital wins ‘Top Global Winner’ at the UNIVANTS awards

This week, it was announced that work to improve HIV outcomes at Croydon Hospital was awarded ‘Top Global Winner’ at the UNIVANTS 2021 awards. The work focused on the introduction of ‘opt-out’ HIV testing in the Emergency Department at Croydon Hospital, with a sustained rate of 97% over 18 months, setting an international gold standard. […]

Read more