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Gastric parietal cell (GPC) antibodies

Category Immunology and PRU
Reporting frequency 3 days

Additional information

GPC antibodies are found in 80% of patients with pernicious anaemia, but are also found in up to 10% of healthy individuals.

GPC antibodies are no longer recommended for investigation of pernicious anaemia due to a lack of specificity. Instead, if a patient is being investigated for pernicious anaemia, intrinsic factor antibodies should be requested.

For more information, refer to the British Society of Haematology Guidelines.

 

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