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Scl-70 antibodies

Category Immunology and PRU
Reporting frequency Weekly

Additional information

Possible clinical association – Systemic sclerosis. Specimens showing a positive ANA will be tested for antibodies to appropriate specific antigens; homogeneous patterns will typically be tested for antibodies to double stranded DNA and speckled patterns will typically be tested for antibodies to the extractable nuclear antigens (RNP, Sm, SSA, and SSB). Other antigen specificities will be tested depending upon the clinical details or if specifically requested.

Reference range: negative <0.95, equivocal 0.95-1.0, positive >1.0

This assay can be requested directly, or may be added on if indicated by the antinuclear antibody (Hep2) result.

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