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Double stranded DNA (dsDNA) antibodies

Category Immunology and PRU
Reporting frequency Weekly

Additional information

Possible clinical association – Diagnosis and monitoring of SLE. Specimens showing a positive ANA will be tested for antibodies to appropriate specific antigens; homogeneous patterns will typically be tested for antibodies to double stranded DNA and speckled patterns will typically be tested for antibodies to the extractable nuclear antigens (RNP, Sm, SSA, and SSB). Other antigen specificities will be tested depending upon the clinical details or if specifically requested.

Reference range: Negative <30 IU/mL, Positive >30 IU/mL

This is a follow-on test that is added on where appropriate, according to the antinuclear antibody (Hep2) results, or by direct request to a Consultant on 0208 725 5106.

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